Small quantity of low concentrated solutions (3 to 6%) Asymptomatic patients who have ingested only a 2.4 First aid measures and management principles Ingestion: Gastric decontamination is not worthwhileįor ingestion of hydrogen peroxide due to its rapidĭissociation. Whitening of the skinĪnd mucous membranes and pain may be signs of exposure. Vomiting of frothy material and gas embolism can help theĭiagnosis if the exposure is not known. 2.3 Diagnosis Gastrointestinal (GI) irritation possibly accompanied by Rectal: rectal bleeding, nausea, distension and difficulty Intravenous: vomiting, pain at injection site, ventricularįibrillation, embolism of heart and lung tissue, haemolyticĪnaemia, renal failure and death. Staining of the cornea, decreased vision, cornal opacity and Solution to the eye (on contact lenses) including punctuate Temporary cornal injury resulting from application of 3% With more concentrated solutions effects may Hyperaemia, lacrimation and severe pain which resolves withinĪ few hours. Ocular: Irritation with a burning sensation, conjunctival The skin usually resolved within a few hours. Inflammation of the respiratory tract Dermal: Irritant to the skin with paraesthesia, blisteringĪnd whitening solutions >10% may cause burns. Solutions there may be more severe irritation and Inhalation: Transient dyspnoea and cough, with concentrated Severe cases ischaemic ECG changes and EMD (electromechanicalĭissociation) may be observed because of embolisation of the Gas embolism has been reported in adults and children. Severe and resolve with symptomatic treatment. Lethargy, coma, convulsions, shock, and respiratory arrest Oxygen - risk of aspiration), haematemesis, 'burningœ throatĪnd gastric distension (due to the release of oxygen). Vomiting (the vomitus may be frothy due to the liberation of 2.2 Summary of clinical effects Ingestion: These effects may occur with solutions ofģ% but usually only where a large quantity has been ingested,Įffects are generally more severe if a concentrated solution Risk of gas embolism is probably also increased with theĬoncentrated solutions, although a large quantity of a dilute Serious because of the risk of more severe irritation. Particularly 30 to 40% and above) should be regarded as Ingestion of the more concentrated solutions (>10%, but In most cases the exposures were to concentrated A number of deaths have been reported in the Irritation, the severity of which depends on theĬoncentration of the solution. SUMMARY 2.1 Main risks and target organs The dissociation of hydrogen peroxide is a violent andĮxothermic reaction. UN2014 (DOT) UN2015 (DOT) UN2984 (DOT) NIOSH/rtecs: MX0900000 1.5 Main brand names, main trade names 1.6 Main manufacturers, main importers 2. Waterstofperoxyde 1.4 Identification numbers 1.4.1 CAS number NAME 1.1 Substance Hydrogen peroxide 1.2 Group Oxygen and compounds Peroxide 1.3 Synonyms Albone Albone 35 This Monograph contain the following sectionsġ. International Programme on Chemical Safety AUTHOR(S), REVIEWER(S), DATE(S) (INCLUDING UPDATES), COMPLETE ADDRESS(ES) TOXICOLOGICAL ANALYSES AND BIOMEDICAL INVESTIGATIONSĨ.1.2 Storage of laboratory samples and specimensĨ.1.3 Transport of laboratory samples and specimensĨ.2 Toxicological Analyses and Their InterpretationĨ.2.1 Tests on toxic ingredient(s) of materialĨ.2.1.2 Advanced Qualitative Confirmation Test(s)Ĩ.2.2.2 Advanced Qualitative Confirmation Test(s)Ĩ.2.3 Interpretation of toxicological analysesĨ.3 Biomedical investigations and their interpretationĨ.3.4 Interpretation of biomedical investigationsĨ.4 Other biomedical (diagnostic) investigations and their interpretationĨ.5 Overall interpretation of all toxicological analyses and toxicological investigationsĩ.4 Systematic description of clinical effectsĩ.4.9 Eye, ear, nose, throat: local effectsĩ.4.12.2 Fluid and electrolyte disturbancesġ0.2 Life supportive procedures and symptomatic/specific treatmentġ4. NAMEĢ.4 First aid measures and management principlesĦ.3 Biological half-life by route of exposureĨ. Hydrogen peroxide (PIM 946) Hydrogen peroxide 1.
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